Avlani VA, Gregory KJ, Morton CJ, Parker MW, Sexton PM, Christopoulos A (2007) Critical role for the second extracellular loop in the binding of both orthosteric and allosteric G protein-coupled receptor ligands. J. Biol. Chem. 282, 25677-25686. Link to article.

Lee HJ, Mun H-C, Lewis NC, Crouch MF, Culverston EL, Mason RS, Conigrave AD (2007) Allosteric activation of the extracellular Ca2+-sensing receptor by L-amino acids enhances ERK 1/2 phosphorylation. Biochem. J. 404, 141-149. Link to article.

Leroy D, Missotten M, Waltzinger C, Martin T, Scheer A (2007) G Protein-coupled receptor-mediated ERK 1/2 phsophorylation: towards a generic sensor for GPCR activation. J. Recept. Sig. Trans. 27, 83-97. Link to article.

May LT, Avlani VA, Langmead CJ, Herdon HJ, Wood MD, Sexton PM, Christopoulos A (2007) Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptors. Mol. Pharmacol. 72, 463-476. Link to article.

Van der Westhuizen ET, Werry TD, Sexton PM, Summers RJ (2007) The relaxin family peptide receptor 3 activates extracellular signal-regulated kinase 1/2 through a protein kinase C-dependant mechanism. Mol. Pharmacol. 71, 1618-1629. Link to article.

Emery B, Merson TD, Snell C, Young KM, Ernst M, Kilpatrick TJ (2006) SOCS3 negatively regulates LIF signaling in neural precursor cells. Mol. Cell. Neurosci. 31, 739-747. Link to article.

Heinrich JN, Brennan J, Lai MH, Sullivan K, Hornby G, Popiolek M, Jiang L-X, Pausch MH, Stack G, Marquis KL, Andree TH (2006) Aplindore (DAB-452), a high-affinity selective dopamine D2 receptor partial agonist. Eur. J. Pharmacol. 552, 36-45. Link to article.

Tang Y, Zhou L, Gunnet JW, Wines PG, Cryan EV, Demarest KT (2006) Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A. Biochem. Biophys. Res. Comm. 345, 29-37. Link to article.

Osmond RIW, Sheehan A, Borowicz R, Barnett E, Harvey G, Turner C, Brown A, Crouch MF, Dyer AR (2005) GPCR screening via ERK 1/2: a novel platform for screening G protein-coupled receptors. J. Biomol. Screen. 10, 730-737. Link to article.

Chong MP, Barritt GJ, Crouch MF (2004) Insulin potentiates EGFR activation and signaling in fibroblasts. Biochem. Biophys. Res. Comm. 322, 535-541. Link to article.

Last updated: September 2011